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At 24 hrs the plasma levels of sildenafil were being continue to about 200 ng/mL, compared to close to five ng/mL when sildenafil was dosed by itself. This can be in step with ritonavir's marked results with a broad variety of P450 substrates. VIAGRA had no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS].T